I’ve just started playing with Tarpipe.  It lets you upload items to several targets/sites in one go.  In about ten minutes I managed to configure it so that I could send a photo to Flickr, tweet a corresponding url to Twitter, a entry to Plurk and send the same photo to Evernote Web.  You can see what it looks like below – sort of like Yahoo Pipes. I’m a PC so i have to upload via email, but for macs there’s Dropipe a desktop widget that files can just be dropped into.  Worth a look.

Tarpipe Workflow